Read10X_h5 fails due to hdf5r issues (libhdf5_hl.so.200)

[SuhasSrinivasan]

Documenting this bug and workarounds for others who may be facing the same issue.

The Read10X_h5 function fails to work since there are two issues due to the combination of CentOS 7 and hdf5r 1.3.5 (latest).
The first issue blocks installation and the second issue blocks loading respectively.

These issues along with their workaround were reported to the hdf5r repo:
hhoeflin/hdf5r#188

[saketkc]

Thanks for opening the issues @SuhasSrinivasan, however since the underlying issue is tied to hdf5r, we will close this here. Hopefully it will get resolved on its own once the rpm/deb repositories are updated.

[SuhasSrinivasan]

Hi @saketkc
Just wanted to check if rhdf5 (Bioconductor) can be a better backend rather than hdf5r.
Since rhdf5 is not dependent on OS-based HDF5 libraries, it installs and works fine on older systems e.g,. CentOS 7.

[saketkc]

Totally possible, though we currently do not want to depend on BioC as it will add another layer of complexity during installation.

[SuhasSrinivasan]

Thank you!