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David Jones committed Mar 27, 2018
2 parents e09a832 + e2a221d commit 41875ed
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168 changes: 113 additions & 55 deletions CHANGES.md
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# CHANGES

## v5.3.4
## v5.3.5
* Update `samtols` and `hstlib` to v1.7
* Update `Bio::DB::HTS` to v2.10
* Change tabix->query call to tabix->query_full
* fixed bug in accessing chr prefixed chromosome names for HDR regions

## v5.3.4
* corrected typo in setup.sh removed safelist branches from .travis
* Added checks for INST_METHOD
* Changed CHANGES.md syntax to markdown linter
* Exonerate install is now skipped if INST_METHOD is 2
* Exonerate install is now skipped if INST_METHOD is 2

## v5.3.2

## v5.3.2
* Fixed bug which caused incorrent assignment of mutant reads overlapping deletion regions to Unknon category - if there is any mismatch in 3prime region from deletionstart site
* Fixed bug which caused incorrent assignment of mutant reads overlapping deletion regions to Unknon category - if there is any mismatch in 3prime region from deletionstart site

## v5.2.2

## v5.2.2
* Heade line for SAMPLE is now generated from command line
* Fixed bug for missing header data when running with bedonly option

## v5.2.1
## v5.2.1

* added condition to test vcf extension when bed file is not present

## v5.2.0
## v5.2.0

* added functionality to process bed file per chromosome
* progress file check during concatenation step ignores already processed chromosomes
* vcf file extension is optional if --bedOnly option is selected

## v5.1.3
## v5.1.3

* Fixed broken INFO tags in vcf and tsv
* tags -t option is now only applicable to tsv file

## v5.1.2

## v5.1.2

* forced default shell to bash for syste command

## v5.1.1
## v5.1.1

* Added custom sorting for vcf files

## v5.1.0
## v5.1.0

* User can now run per chromosome analysis [useful to run in parallel ] and concatenate the resulting files

## v5.0.0
## v5.0.0

* Removed exonerate parameter to filter alignments based on score
* Removed condition to discard alignment length smaller than read length
* Added user defined option to specify exonerat percent value
* Added user defined option to specify exonerat percent value
* Increased padding to extended reference sequence -- this will allow to map longer reads in amplicon data.

## v4.5.6
## v4.5.6

* Update to Bio::DB::HTS install to use already installed htslib

## v4.5.5
## v4.5.5

* updated version tag

## v4.5.4
## v4.5.4

* Removed default high depth regions filter option, users can optionally provide this file on command line (refer wiki)

## v4.5.3 * Updated licensing policy

* Added option to supply external ignore depth file
* removed legacy code to run external commands
* Added prerelease.sh to

## v4.5.2
## v4.5.2

* Updated .gitignore to allow test data to be added to git

## v4.5.1
## v4.5.1

* Updated test data set files

## v4.5.0
## v4.5.0

* Added option to restrict reads based on mapping quality threshold

## v4.4.2
## v4.4.2

* Exonerate --percent threshold reduced to 90 from 95 to allow 4 mismatches

## v4.4.1
## v4.4.1

* More robust check for mismatches at varinat positions in the alignment

## v4.4.0
## v4.4.0

* added additional condition to check mismatch at the variant region in the alignment
* reads mapping on alternate sequence and have mismatch at variant region were categorised into UNK [ unknown ] reads
* updated option to correctly read bed file

## v4.3.6
## v4.3.6

* Creates augmented vcf file even if no records were augmented
* Corrected processlog in vcf output header

## v4.3.5
## v4.3.5

* Minor change to test script

## v4.3.4
## v4.3.4

* Appropriate warning message when no vcf file found for a sample

## v4.3.3
## v4.3.3

* updated changes.md and verision information

## V4.3.2
## V4.3.2

* corrected tabix syntax as for Bio::DB::HTS::Tabix, added test for high depth region overlap

## V4.3.1
## V4.3.1

* removed legacy script from Makefile

## V4.3.0
## V4.3.0

* removed database dependecy code for external release

## V4.2.3
## V4.2.3

* replaced Tabix with Bio::DB::HTS::Tabix

## V4.2.2
## V4.2.2

* changed Bio::DB::HTS version to 1.12

## V4.2.1
## V4.2.1

* changed Bio::DB::HTS version to 1.11

## V4.2.0
## V4.2.0

* Added support to Bio::DB::HTS

## V4.1.17
## V4.1.17

* Updated SQL query to get input data to generate commands

## V4.1.16
## V4.1.16

* corrected condition to get unmatched normal

## V4.1.15
## V4.1.15

* Fixed vcf header, as it was copied twice in the outfile

## V4.1.14
## V4.1.14

* Added explicit check for normal sample using SIP_ATTRIBUTES table

## V4.1.13
## V4.1.13

* updated defualt project ini folder to cgpVaf

## V4.1.12
## V4.1.12

* Updated verison

## V4.1.11
## V4.1.11

* Added condition to ignore writing progress file if augment only option is selected

## V4.1.10
## V4.1.10

* Improved and corrected setup.sh and location of Makefile.PL

## V4.1.8
## V4.1.8

*added test to check final result removal
*chnaged bio:db:sam version to 1.42

## V4.1.7
## V4.1.7

*changed installation path to bin from perl/bin in setup.sh

## V4.1.6
## V4.1.6

*fixed test to created progress file path

## V4.1.5
## V4.1.5

*updated condition to create outfile only if it is absent

## V4.1.4
## V4.1.4

*updated file postfix to <varinat>_vaf

## V4.1.3
## V4.1.3

*Added tumour sample name as postfix to tmp folder

## V4.1.2
## V4.1.2

*Added setup.sh

## V4.1.1
## V4.1.1

*Fixed bug in unmapped mate retrival

## V4.1.0
## V4.1.0

*Added option to accept vcf file as command line input

## V4.0.1
## V4.0.1

* Fixed readme file

## V4.0
## V4.0

* Contains pre-calculated VAF values in FORMAT field
* Per chromosome progress tracking i.e., failed jobs can be resumed from last unsuccessful chromosome
* Added setup script script

## 3.2.4
## 3.2.4

* Added condition to check snps that fall at the end of chromosome

## 3.2.3 * Added option to create config file for user defined list of samples
## 3.2.3

* Added option to create config file for user defined list of samples
2 changes: 1 addition & 1 deletion perl/Makefile.PL
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Expand Up @@ -28,7 +28,7 @@ WriteMakefile(
EXE_FILES => [qw( bin/cgpVaf.pl )],
PREREQ_PM => {
'Attribute::Abstract' => '1.02',
'Bio::DB::HTS' => '1.12',
'Bio::DB::HTS' => '2.10',
'Bio::Root::Version' => '1.006924',
'Capture::Tiny' => '0.24',
'Config::IniFiles' => '2.83',
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3 changes: 1 addition & 2 deletions perl/lib/Sanger/CGP/Vaf.pm
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Expand Up @@ -2,7 +2,7 @@ package Sanger::CGP::Vaf;
use strict;
use Const::Fast qw(const);

our $VERSION = '5.3.4';
our $VERSION = '5.3.5';

const my $LICENSE =>
"#################
Expand All @@ -16,4 +16,3 @@ sub license {
}

1;

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