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# CHANGES | ||
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## v5.3.4 | ||
## v5.3.5 | ||
* Update `samtols` and `hstlib` to v1.7 | ||
* Update `Bio::DB::HTS` to v2.10 | ||
* Change tabix->query call to tabix->query_full | ||
* fixed bug in accessing chr prefixed chromosome names for HDR regions | ||
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## v5.3.4 | ||
* corrected typo in setup.sh removed safelist branches from .travis | ||
* Added checks for INST_METHOD | ||
* Changed CHANGES.md syntax to markdown linter | ||
* Exonerate install is now skipped if INST_METHOD is 2 | ||
* Exonerate install is now skipped if INST_METHOD is 2 | ||
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## v5.3.2 | ||
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## v5.3.2 | ||
* Fixed bug which caused incorrent assignment of mutant reads overlapping deletion regions to Unknon category - if there is any mismatch in 3prime region from deletionstart site | ||
* Fixed bug which caused incorrent assignment of mutant reads overlapping deletion regions to Unknon category - if there is any mismatch in 3prime region from deletionstart site | ||
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## v5.2.2 | ||
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## v5.2.2 | ||
* Heade line for SAMPLE is now generated from command line | ||
* Fixed bug for missing header data when running with bedonly option | ||
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## v5.2.1 | ||
## v5.2.1 | ||
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* added condition to test vcf extension when bed file is not present | ||
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## v5.2.0 | ||
## v5.2.0 | ||
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* added functionality to process bed file per chromosome | ||
* progress file check during concatenation step ignores already processed chromosomes | ||
* vcf file extension is optional if --bedOnly option is selected | ||
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## v5.1.3 | ||
## v5.1.3 | ||
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* Fixed broken INFO tags in vcf and tsv | ||
* tags -t option is now only applicable to tsv file | ||
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## v5.1.2 | ||
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## v5.1.2 | ||
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* forced default shell to bash for syste command | ||
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## v5.1.1 | ||
## v5.1.1 | ||
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* Added custom sorting for vcf files | ||
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## v5.1.0 | ||
## v5.1.0 | ||
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* User can now run per chromosome analysis [useful to run in parallel ] and concatenate the resulting files | ||
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## v5.0.0 | ||
## v5.0.0 | ||
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* Removed exonerate parameter to filter alignments based on score | ||
* Removed condition to discard alignment length smaller than read length | ||
* Added user defined option to specify exonerat percent value | ||
* Added user defined option to specify exonerat percent value | ||
* Increased padding to extended reference sequence -- this will allow to map longer reads in amplicon data. | ||
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## v4.5.6 | ||
## v4.5.6 | ||
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* Update to Bio::DB::HTS install to use already installed htslib | ||
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## v4.5.5 | ||
## v4.5.5 | ||
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* updated version tag | ||
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## v4.5.4 | ||
## v4.5.4 | ||
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* Removed default high depth regions filter option, users can optionally provide this file on command line (refer wiki) | ||
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## v4.5.3 * Updated licensing policy | ||
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* Added option to supply external ignore depth file | ||
* removed legacy code to run external commands | ||
* Added prerelease.sh to | ||
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## v4.5.2 | ||
## v4.5.2 | ||
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* Updated .gitignore to allow test data to be added to git | ||
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## v4.5.1 | ||
## v4.5.1 | ||
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* Updated test data set files | ||
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## v4.5.0 | ||
## v4.5.0 | ||
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* Added option to restrict reads based on mapping quality threshold | ||
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## v4.4.2 | ||
## v4.4.2 | ||
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* Exonerate --percent threshold reduced to 90 from 95 to allow 4 mismatches | ||
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## v4.4.1 | ||
## v4.4.1 | ||
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* More robust check for mismatches at varinat positions in the alignment | ||
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## v4.4.0 | ||
## v4.4.0 | ||
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* added additional condition to check mismatch at the variant region in the alignment | ||
* reads mapping on alternate sequence and have mismatch at variant region were categorised into UNK [ unknown ] reads | ||
* updated option to correctly read bed file | ||
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## v4.3.6 | ||
## v4.3.6 | ||
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* Creates augmented vcf file even if no records were augmented | ||
* Corrected processlog in vcf output header | ||
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## v4.3.5 | ||
## v4.3.5 | ||
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* Minor change to test script | ||
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## v4.3.4 | ||
## v4.3.4 | ||
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* Appropriate warning message when no vcf file found for a sample | ||
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## v4.3.3 | ||
## v4.3.3 | ||
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* updated changes.md and verision information | ||
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## V4.3.2 | ||
## V4.3.2 | ||
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* corrected tabix syntax as for Bio::DB::HTS::Tabix, added test for high depth region overlap | ||
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## V4.3.1 | ||
## V4.3.1 | ||
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* removed legacy script from Makefile | ||
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## V4.3.0 | ||
## V4.3.0 | ||
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* removed database dependecy code for external release | ||
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## V4.2.3 | ||
## V4.2.3 | ||
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* replaced Tabix with Bio::DB::HTS::Tabix | ||
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## V4.2.2 | ||
## V4.2.2 | ||
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* changed Bio::DB::HTS version to 1.12 | ||
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## V4.2.1 | ||
## V4.2.1 | ||
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* changed Bio::DB::HTS version to 1.11 | ||
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## V4.2.0 | ||
## V4.2.0 | ||
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* Added support to Bio::DB::HTS | ||
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## V4.1.17 | ||
## V4.1.17 | ||
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* Updated SQL query to get input data to generate commands | ||
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## V4.1.16 | ||
## V4.1.16 | ||
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* corrected condition to get unmatched normal | ||
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## V4.1.15 | ||
## V4.1.15 | ||
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* Fixed vcf header, as it was copied twice in the outfile | ||
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## V4.1.14 | ||
## V4.1.14 | ||
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* Added explicit check for normal sample using SIP_ATTRIBUTES table | ||
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## V4.1.13 | ||
## V4.1.13 | ||
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* updated defualt project ini folder to cgpVaf | ||
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## V4.1.12 | ||
## V4.1.12 | ||
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* Updated verison | ||
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## V4.1.11 | ||
## V4.1.11 | ||
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* Added condition to ignore writing progress file if augment only option is selected | ||
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## V4.1.10 | ||
## V4.1.10 | ||
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* Improved and corrected setup.sh and location of Makefile.PL | ||
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## V4.1.8 | ||
## V4.1.8 | ||
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*added test to check final result removal | ||
*chnaged bio:db:sam version to 1.42 | ||
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## V4.1.7 | ||
## V4.1.7 | ||
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*changed installation path to bin from perl/bin in setup.sh | ||
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## V4.1.6 | ||
## V4.1.6 | ||
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*fixed test to created progress file path | ||
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## V4.1.5 | ||
## V4.1.5 | ||
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*updated condition to create outfile only if it is absent | ||
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## V4.1.4 | ||
## V4.1.4 | ||
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*updated file postfix to <varinat>_vaf | ||
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## V4.1.3 | ||
## V4.1.3 | ||
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*Added tumour sample name as postfix to tmp folder | ||
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## V4.1.2 | ||
## V4.1.2 | ||
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*Added setup.sh | ||
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## V4.1.1 | ||
## V4.1.1 | ||
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*Fixed bug in unmapped mate retrival | ||
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## V4.1.0 | ||
## V4.1.0 | ||
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*Added option to accept vcf file as command line input | ||
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## V4.0.1 | ||
## V4.0.1 | ||
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* Fixed readme file | ||
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## V4.0 | ||
## V4.0 | ||
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* Contains pre-calculated VAF values in FORMAT field | ||
* Per chromosome progress tracking i.e., failed jobs can be resumed from last unsuccessful chromosome | ||
* Added setup script script | ||
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## 3.2.4 | ||
## 3.2.4 | ||
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* Added condition to check snps that fall at the end of chromosome | ||
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## 3.2.3 * Added option to create config file for user defined list of samples | ||
## 3.2.3 | ||
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* Added option to create config file for user defined list of samples |
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